Immunotherapy reverses immune aging in mice, restoring balance

Livescience.com March 27, 2024, 05:00 PM UTC

Summary: A new immunotherapy targets aging immune cells in mice, potentially reversing immune aging. The treatment disrupts the bias towards myeloid cells over lymphoid cells as we age. Researchers developed an antibody therapy that destroys myeloid hematopoietic stem cells, restoring balance and promoting a more youthful immune system. Treated mice showed increased adaptive immune cells and reduced inflammation. The study, published in Nature, shows promise for human application.

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    Treatment depleting my-HSCs rejuvenates aged mice immune system (News-Medical.Net)
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