Brain inflammation and DNA damage crucial for memory formation
Neuroscience News — March 27, 2024, 07:00 PM UTC
Summary: Researchers at Albert Einstein College of Medicine discovered that brain inflammation and DNA damage in hippocampal neurons are crucial for long-term memory formation, challenging conventional beliefs. The Toll-Like Receptor 9 (TLR9) pathway plays a key role in this process. Inhibiting TLR9 may hinder memory encoding and lead to genomic instability. The study emphasizes caution in targeting this pathway for therapeutic purposes.
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