Vaccine strategy generates HIV neutralizing antibodies

Summary: A team at Duke Human Vaccine Institute developed a vaccine approach, published in Cell Host & Microbe, guiding the immune system to produce broadly neutralizing antibodies against HIV. By adding sequential mutations to an engineered antibody, they created a vaccine providing step-by-step directions. The strategy could be applied to vaccines for other diseases. The study received funding from the National Institute of Allergy and Infectious Diseases.

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