Trinity College Dublin enhances MRSA vaccine efficacy with IL-10

Trinity College Dublin researchers have discovered that targeting the immune molecule IL-10 during vaccine delivery enhances MRSA vaccine efficacy. MRSA causes over one million deaths annually worldwide, with antibiotic resistance on the rise. The study, led by Professor Rachel McLoughlin, showed improved immune response and bacterial clearance in an animal model by neutralizing IL-10 alongside vaccination. This breakthrough offers hope for more effective S. aureus vaccines.