Small molecule OXF-077 combats antibiotic resistance by inhibiting SOS response

Researchers at the University of Oxford have discovered a small molecule, OXF-077, that suppresses antibiotic resistance in bacteria by inhibiting the SOS response. This molecule enhances the effectiveness of antibiotics against drug-resistant bacteria like MRSA. The study, published in Chemical Science, offers hope in combating the global threat of antibiotic resistance, which currently causes 1.27 million deaths annually. Further research is ongoing to develop new strategies against antibiotic resistance.