Researchers develop new method to map gene activity in living human brain

Researchers have created a new method to map gene activity in the living human brain, focusing on epilepsy. This technique uses RNA and DNA from electrodes implanted in patients, linking gene activity to electrical recordings of seizures. The method improves understanding of seizure networks, which may enhance the accuracy of epilepsy surgeries for patients who do not respond to medication. It also has potential applications for studying other neurological disorders like Alzheimer’s and Parkinson’s. This research, published in JCI Insight, was led by FutureNeuro and involved international collaboration. It marks a significant advancement in neuroscience, allowing for non-invasive profiling of gene activity in the brain.