Psilocybin changes brain connectivity for weeks

A new study reveals that psilocybin, a psychedelic compound, alters brain network connectivity for weeks after a single dose. This could explain its potential as a psychiatric therapy. Researchers found that psilocybin disrupts communication between brain networks, particularly the hippocampus and default mode network. These effects, distinct from methylphenidate, were reproducible over time in the study participants. The study, published in Scientific Data, used advanced imaging techniques to analyze the effects of psilocybin in healthy adults. The findings may help refine its therapeutic use for mental health conditions.