Over 5,000 cancer-linked gene variants discovered, potential treatment target
Summary: A study revealed over 5,000 genetic variations linked to cancer growth, focusing on the BAP1 gene. Nearly one-fifth of these mutations were found to increase the risk of malignancies in various organs. The findings, published in Nature Genetics, aim to aid in diagnosing patients and developing effective therapies. Researchers also identified a potential therapeutic target related to IGF-1 levels. The study's comprehensive approach benefits diverse populations.
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