New imaging technique tracks drug delivery with nanoparticles

Researchers at Waseda University in Tokyo have developed a new imaging technique that allows for real-time tracking of gold nanoparticles (AuNPs) in the body. This method uses neutron activation to make the nanoparticles detectable without external tracers, improving accuracy. Traditional imaging methods often rely on tracers that can detach from the nanoparticles, leading to inaccurate results. The new technique transforms stable gold into a radioactive form, enabling long-term visualization of drug delivery in cancer therapy. The study demonstrated this method by tracking radioactive AuNPs in tumor-bearing mice, allowing for extended monitoring of a radiotherapeutic drug. This advancement could enhance targeted drug delivery and improve the effectiveness of cancer treatments.