Man in Israel finds relief from rare condition causing allergy to his own orgasms
dailymail.co.uk — February 4, 2025, 11:00 PM UTC
A 22-year-old man in Israel has been diagnosed with postorgasmic illness syndrome (POIS), a rare condition affecting about 50 people globally. He experienced severe symptoms like fatigue and muscle pain after orgasms since he was 14. After years of suffering, he sought medical help and tested negative for a semen allergy. Doctors suspect his symptoms may be linked to immune cells reacting during orgasms. He was treated with omalizumab, a medication that blocks allergic reactions. After seven months of treatment, his symptoms ceased, allowing him to engage in normal relationships.