Leptin reverses diabetic ketoacidosis without insulin

neurosciencenews.com

Leptin, a hormone signaling energy sufficiency, can reverse diabetic ketoacidosis without insulin, researchers confirm. The brain, misinterpreting low leptin as a lack of fuel, triggers DKA. Leptin administration in animal models normalized blood sugar and ketone levels, suggesting brain-based diabetes treatment. This discovery challenges the century-old insulin-centric model of type 1 diabetes and could lead to insulin-free therapies.


With a significance score of 3.7, this news ranks in the top 5% of today's 23048 analyzed articles.

Get summaries of news with significance over 5.5 (usually ~10 stories per week). Read by 10,000+ subscribers:


Leptin reverses diabetic ketoacidosis without insulin | News Minimalist