Eva1 CAR-T cells eliminated tumors in mice

A preclinical study demonstrated that Eva1-targeted CAR-T cells successfully eliminated tumors in lab mice, offering a potential new treatment for various cancers. Researchers developed genetically modified immune cells (CAR-T cells) to target the Eva1 protein, abundant on lung, pancreatic, and liver cancer cells. The treatment, detailed in the Journal for ImmunoTherapy of Cancer, showed effectiveness and safety in mice. The study's success paves the way for potential human trials, focusing on cancers that are difficult to treat. Researchers are now working to confirm the treatment's safety before moving toward clinical application.