tARC-seq technology reveals SARS-CoV-2 mutation hotspots accurately

Summary: Scientists at Baylor College of Medicine developed tARC-seq, a new technology, to calculate SARS-CoV-2's mutation rate. The study in Nature Microbiology revealed mutation hotspots in the spike protein RNA, aiding in understanding the virus's evolution. tARC-seq detected rare mutations in low-abundance samples, showing higher-than-expected mutation rates. This technology helps monitor viral evolution, crucial for pandemic surveillance and vaccine development.

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