COVID-19 variant PJ.2.1 spreads globally; symptoms and risks explained

A new COVID-19 variant, PJ.2.1, first detected in Canada in May 2026, is spreading globally, prompting close monitoring by the World Health Organization due to its growing geographical reach. The variant, described as a "novel saltation variant" in an October 2026 study, has a heavily mutated spike protein and increased cell-entry efficiency, but shows no evidence of causing more severe illness or substantially escaping vaccine-induced antibodies. It has been found in the US, Australia, Singapore, and Spain. Symptoms resemble a common cold or flu, requiring diagnostic tests for identification. Experts advise testing when symptomatic, staying up to date with vaccinations, and avoiding close contact while unwell, as its full impact remains uncertain.