Chinese scientists study peptide aggregation for drug stability
phys.org — September 3, 2024, 06:00 AM UTC
Summary: Chinese scientists have studied the aggregation of short peptide chains, focusing on 160,000 tetrapeptides and 3.2 million pentapeptides. Their research, published in JACS Au, reveals that aromatic amino acids enhance aggregation, while hydrophilic ones inhibit it. The findings could impact drug stability, material science, and understanding diseases like Alzheimer's, highlighting the role of AI in predicting peptide behavior.
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