Cancer drugs may treat Alzheimer's, mouse study suggests
Researchers have identified two cancer drugs that show promise in slowing or reversing Alzheimer's symptoms in mice, potentially offering a new treatment approach. The drugs, used to treat breast, colon, and lung cancers, were found to improve memory and reverse brain degeneration in the study. The study, published Monday, involved screening over 1,300 drugs and found that a combination of letrozole and irinotecan showed the most potential. The researchers hope to conduct clinical trials with Alzheimer's patients, as current treatments have limited effectiveness. Alzheimer's disease, with no cure, is marked by gene expression changes in the brain. The cancer drugs may work by influencing gene expression and reducing inflammation, but further research is needed to understand their mechanisms and side effects.