Autism risk genes converge into two brain patterns, guiding targeted therapy

New research published in Science reveals that despite over 1,200 genes linked to autism spectrum disorder, brain changes converge into just two distinct molecular patterns, offering a new framework for understanding the condition. The study identifies two molecular states that autism risk genes split into, which may guide precision therapy approaches tailored to specific subtypes of the disorder rather than treating it as a single condition. These findings could help researchers develop targeted treatments based on which of the two molecular pathways is disrupted in an individual, potentially improving therapeutic outcomes for the diverse autism population.