New chemical tool visualizes neuronal signaling for drug targeting

Summary: Researchers at the University of Michigan developed a new chemical tool to study how signals like dopamine and epinephrine interact with neurons via G protein-coupled receptors (GPCRs). This tool enables detailed visualization of GPCR-related signals across the entire brain with high spatial resolution, offering insights into neuronal signaling and drug targeting. The tool marks cells with a permanent fluorescent signal, facilitating the study of signal pathways at a cellular level.

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