Epigenetic changes in Alzheimer's patients' immune system may offer therapy targets

A new study from Northwestern University reveals epigenetic alterations in the immune system of Alzheimer’s patients’ blood, potentially influenced by environmental or behavioral factors. The research indicates these changes affect genes associated with Alzheimer’s susceptibility and could be targeted for therapy. The study, published in Neuron, suggests the peripheral immune system’s role in Alzheimer’s progression and identifies potential therapeutic targets. The research is supported by NIH grants and other foundations.