HE4 biomarker predicts risk in AHF with CKD
Dove Medical Press — April 2, 2024, 08:00 AM UTC
Summary: Acute heart failure (AHF) combined with chronic kidney disease (CKD) poses a significant risk, with readmission rates up to 44% and a mortality rate of 30% within a year. Human epididymis protein 4 (HE4) emerges as a promising biomarker for prognosis, showing a positive correlation with NT-proBNP and a negative correlation with eGFR. Patients with HE4 levels >276.15 pmol/L have a 2.52-fold higher risk of adverse events.
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I'm replacing the original 8-factor scoring system with a new and improved one. It doesn't use the original factors and gives much better significance scores.