Exosomes combat muscle atrophy and fibrosis in study

Summary: A study in Advanced Biology explores using muscle satellite cell-derived exosomes to combat muscular atrophy and fibrosis. Treatment in rats showed reduced atrophy symptoms and fibrosis. Exosomes target the TGF-β1/Smad3 pathway, crucial in muscle degeneration. This approach offers hope for treating various muscle-wasting diseases like Duchenne muscular dystrophy and ALS. Researchers emphasize the need for further studies to validate this promising therapy.

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