Brain pH and lactate levels linked to neuropsychiatric disorders

Summary: A global study involving 131 researchers from 105 labs across seven countries reveals altered brain pH and lactate levels in 30% of animal models of neuropsychiatric disorders. These changes are linked to impaired working memory, suggesting a common energy metabolism dysfunction in conditions like schizophrenia, autism, and Alzheimer’s. The findings offer new insights for developing targeted treatments.

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