Scientists used a spatial light modulator to turn an iPhone 14 Pro image into a 3D hologram. The study, published in Optics Letters, detailed a "cascade of holograms" technique. Incoherent light from smartphones was used, eliminating speckle noise caused by lasers. This cost-effective method could lead to holographic displays for AR/VR devices. Lead author Ryoichi Horisaki from the University of Tokyo explained the innovative approach.

A Harvard University study of 114,000 participants over 30 years found consuming ultra-processed foods (UPF) increases the risk of death. Ready-to-eat meats, sugary drinks, and highly processed breakfast foods showed the strongest associations. Diets high in UPFs were linked to a 4% higher chance of mortality. UPFs can lead to various health issues, emphasizing the need to limit their consumption for better health and longevity.

Chinese scientists found sea surface temperature anomalies in the tropical Indian Ocean can predict global dengue epidemics' magnitude. Dengue affects half the world's population. Climate events like El Nino impact dengue transmission. Models can now predict outbreaks up to nine months in advance, a significant improvement from previous three-month forecasts. This could enhance outbreak response planning. Further evaluation of the model's predictive performance is required.

Scientists at UC Riverside and Clarkson University developed a new method combining UV light treatment, sulphite, and electrochemical oxidation to effectively clean up PFAS pollution from fire suppressant foams. The strategy achieved near-complete destruction of PFAS in contaminated water samples. PFAS pollution from fire suppression foams is a significant issue at military sites and airports. The method, detailed in Nature Water, offers a solution for treating contaminated groundwater.

Scientists at Trinity College Dublin discovered that the vaccine adjuvant C100, derived from chitin, promotes potent anti-tumour immunity when injected into tumors. Published in Cell Reports Medicine, the study reveals C100's ability to activate a specific signaling pathway without causing inflammation. The research suggests C100 could enhance cancer immunotherapies, potentially improving response rates and offering hope for future immune therapies.

OpenAI's ChatGPT gained popularity in 2022, sparking interest in AI. OpenAI plans to launch an AI-powered Search product to compete with Google, possibly on May 13. The new search capability will enhance ChatGPT's utility by providing answers with citations and visual aids. Despite ChatGPT being seen as a Google Search competitor, its inaccuracies led users to cross-check information. OpenAI's entry into the search market will challenge Google's dominance.

A team at Duke Human Vaccine Institute developed a vaccine approach, published in Cell Host & Microbe, guiding the immune system to produce broadly neutralizing antibodies against HIV. By adding sequential mutations to an engineered antibody, they created a vaccine providing step-by-step directions. The strategy could be applied to vaccines for other diseases. The study received funding from the National Institute of Allergy and Infectious Diseases.

In 2024, HuffPost covers the critical US presidential election for well-informed voters, offering free journalism while other outlets use paywalls. They rely on reader contributions, even as little as $2, to support their impactful reporting on key issues like women's rights, healthcare, and democracy. With Donald Trump facing Joe Biden, HuffPost emphasizes the importance of a free press in shaping America's future.

Stanford researchers are developing a new AI-assisted holographic imaging technology for AR headsets. The prototype boasts a thin design and high-quality 3D images. It uses a unique nanophotonic metasurface waveguide and AI algorithms to enhance image quality. The technology aims to disrupt the spatial computing market dominated by bulky headsets. Postdoctoral researcher Gun-Yeal Lee claims it surpasses current AR systems in capability and compactness.

Josh Tseng, visually impaired due to congenital glaucoma, can now play FPS games like Counter-Strike 2 with JBL Quantum Guide Play software. Developed by JBL and AbleGamers, it uses AI to convert visuals into audio cues for navigation and gameplay. Launched on April 4, the free software alerts players to obstacles, enemies, and teammates through customizable sounds. It will soon be open-source for other games.

Johns Hopkins University researchers have developed the Multifunctional Ablative Gastrointestinal Imaging Capsule (MAGIC), integrating OCT technology, an endoscope camera, and an ablation laser for esophagus surveillance. MAGIC's dual wavelengths of 800 and 1300 nm provide high resolution, aiding in early lesion detection. This advancement addresses limitations of existing technologies, potentially revolutionizing esophageal healthcare globally.

The National Institute of Nutrition, in collaboration with the Indian Council of Medical Research, has released comprehensive dietary guidelines for Indians. Over 56% of non-communicable diseases are linked to an unhealthy diet. Proper nutrition for mothers and children is crucial for preventing diseases like diabetes and heart issues. The guidelines cover ideal diets for pregnant women, infants, adolescents, and the elderly, emphasizing balanced meals and caution against protein supplements.

Scientists have developed a unique porous material, dubbed a 'cage of cages,' to trap greenhouse gases like CO2 and SF6. The material, with high stability and affinity for gases, could aid in capturing and storing emissions. Current carbon removal strategies fall short of needed levels. The material, created through supramolecular self-assembly, shows promise for addressing climate change. The study was published in Nature Synthesis.

The semiconductor industry is poised for transformation with AI PCs using Arm chips, as noted by Morgan Stanley. Microsoft's AI tool Copilot requires PCs with 45 tera operations per second. Arm CPUs are known for energy efficiency, leading to longer battery life. Morgan Stanley predicts a 95% penetration rate of AI PCs by 2027, with WOA PC chip shipments reaching 65 million in 2028. Stocks benefiting include TSMC, MediaTek, Nvidia, Qualcomm, Microsoft, and Arm.

Microsoft will launch a web-based mobile game store in July, offering an alternative to Apple and Google's app stores. The store will initially feature Microsoft games like Candy Crush Saga and later open to other publishers. This move aims to provide a platform accessible across all devices and countries, free from closed ecosystem restrictions. Microsoft's entry into the US$90 billion mobile gaming market follows its US$69 billion acquisition of Activision Blizzard.

Human Rights Watch warns of likely genocide in Sudan due to a year-long civil war causing famine and atrocities. The conflict involves military and paramilitary forces, resulting in ethnic cleansing and crimes against humanity. At least 1.7 million people face hunger, with reports of malnourished children and widespread violence. HRW calls for sanctions and urgent global intervention to protect civilians. UN and AU are urged to act.

UN warns of climate crisis as 80% of experts predict global heating to surpass 1.5C target. Almost 400 IPCC authors surveyed, with only 6% expecting to stay within limit. Urgent action needed to curb fossil fuel use and prevent catastrophic 2.5C rise. Leaders urged to fulfill climate commitments and transition away from fossil fuels. Lack of political will identified as major barrier to climate action. Calls for immediate and transformative policies to prioritize planet and people over profit.

The National Oceanic and Atmospheric Administration's Space Weather Prediction Center raised the geomagnetic storm watch to level G 4 due to four coronal mass ejections heading towards Earth. This rare event could impact satellite communication systems, GPS, and aurora visibility. The storm is expected to hit by May 11, potentially causing voltage control issues and disruptions to the grid. Northern U.S. states have increased chances of seeing the Northern Lights.

A team of scientists reconstructed a millimeter-sized segment of the human brain, containing 57,000 cells, 150 million synapses, and 230 millimeters of ultrafine veins, using 1.4 petabytes of data. This detailed project aims to understand brain function and disorders better. The reconstruction, named H01, revealed new insights, such as glia outnumbering neurons 2:1. The data and reconstruction are freely available online.

Researchers at UCLA developed a new immunotherapy for malignant gliomas, combining a personalized dendritic cell vaccine with poly-ICLC to enhance the immune response. This treatment significantly boosts T cell activity against brain tumors, potentially improving patient outcomes. Initial results show increased interferon response, correlating with longer survival. Further studies are needed to confirm these promising findings. The study was funded by the National Cancer Institute.

In southern Brazil, emergency workers rescued a horse named Caramelo from a rooftop after severe floods, with the death toll at 107. Over 165,000 people have been displaced, and 136 are missing. The state needs $3.68bn for rebuilding. Rescuers have saved about 10,000 animals, with heartwarming reunions shared on social media. The horse rescue involved firefighters, veterinarians, and multiple boats.

NASA has approved further funding for the FLOAT project, aiming to create a lunar railway system by the 2030s. The project involves magnetic robots levitating on a film track, transporting up to 100 tons of material daily at 1 mph on the moon's surface. This initiative is part of NASA's Innovative Advanced Concepts program for future space exploration, alongside other innovative projects like fluid telescopes and plasma-propelled rockets.

Uber's safety features, including PIN verification and ride recording, aim to enhance passenger security. With 9,805 reported sexual assaults from 2017 to 2020, these tools are crucial. Customizable options like scheduling safety features based on time and location provide added protection. Accessing these features in the Uber app involves five simple steps. Additional safety tools like Text-to-911 and Live Help are available during rides.

The Vatican declared the 2025 Jubilee, expecting 32 million pilgrims in Rome. Pope Francis emphasized hope and solidarity in a ceremony. The event aims to improve Rome with €4 billion in public funds. Projects include new parks, repaved piazzas, and a subway extension. Despite delays and traffic disruptions, the mayor assures completion on time. Only two of 231 projects were finished by late April.

Former President Donald Trump offered top US oil executives a deal: $1 billion for his re-election campaign in exchange for overturning environmental regulations. At a dinner, he promised increased oil drilling, removal of hurdles in Alaska, and reversing pollution rules. Environmental groups criticized the transactional nature of the offer. Trump's strong polling despite legal issues and oil companies preparing for his potential return to office were also highlighted.

A CFPB regulation aiming to reduce credit card late fees faces a legal challenge led by the U.S. Chamber of Commerce. The rule would cap late fees at $8 per incident, potentially saving Americans billions. The court in Texas is expected to decide on a freeze before the Tuesday implementation. Late fees have risen since 2010, with users averaging $138 annually. President Biden opposes such "junk fees."

A humanitarian aid shipment from Cyprus to Gaza aims to assist amid a dire situation, with 34,800 Palestinians killed and 80% displaced. The U.S. vessel Sagamore carries aid to Gaza's new pier, built due to land crossing restrictions. President Biden opposes an Israeli invasion of Rafah, offering defensive support. Israeli tensions rise as aid distribution is hindered by closures and ongoing conflict.

A resurgence of whooping cough in England has led to five baby deaths, with 2,793 new cases in Q1 2024 compared to 858 in 2023. The drop in expectant mothers' vaccination rates contributed to the rise. The antenatal vaccine reduced infant deaths by two-thirds since 2012. Vaccination is crucial, with rates dropping from over 70% in 2017 to about 58% in 2023. NHS urges prompt vaccination.

Neuralink's first brain implant in a human had threads retracting but has been fixed. The company plans to install 10 more devices in humans this year. The implant allows cursor control using thoughts, with over 1,000 electrodes and at least 64 threads. Higher bits-per-second (BPS) scores indicate better cursor control. The patient, Noland Arbaugh, paralyzed since 2016, showed improvement after tweaks. Elon Musk confirmed the success on Twitter.

Biodiversity loss is the primary driver of infectious disease outbreaks, as per a meta-analysis in Nature. Loss of species increases outbreak risks the most, followed by climate change and non-native species. Urbanization decreases disease spread due to better sanitation and fewer wildlife. Zoonotic diseases, like Covid-19, often originate in wildlife. Researchers suggest reducing emissions, biodiversity loss, and invasive species to mitigate disease burden globally.

Google DeepMind has launched AlphaFold 3, an AI model that predicts the structures of proteins, DNA, RNA, and ligands with 50% improved accuracy. The model aids research in medicine, agriculture, and drug development. Isomorphic Labs is already benefiting from AlphaFold 3, and DeepMind offers the AlphaFold Server for free to researchers. Google is working on deploying the model responsibly due to concerns about biosecurity risks.

Ukraine faces potential power shutdowns as Russian missiles and drones target energy infrastructure. Ukrenergo warns of blackouts and rationing due to attacks on power plants. Emergency supplies from European countries are being used to overcome shortages. Strikes hit facilities in six regions. Energy Minister condemns the attacks, emphasizing the ongoing threat to Ukraine's energy industry.

New variants KP.2 and KP1.1, known as FLiRT, are descendants of Omicron JN.1. FLiRT cases are rising globally, with 238 KP.2 and 30 KP1.1 cases in India. KP.2 is more prevalent, accounting for 25% of new U.S. cases. It shows increased immune resistance, challenging vaccine protection. Experts recommend updating vaccines. Precautions include hygiene, masks, distancing, and vaccination. COVID-19 remains a concern for public health.

Research shows vaping can produce 127 "acutely toxic" chemicals, 153 "health hazards," and 225 "irritants." Flavoured vapes, popular among non-smoking youth, pose a potential public health threat. The UK government plans to ban disposable vapes and restrict sweet flavours. Experts urge comprehensive regulations to prevent future chronic diseases. Vaping is advised only for tobacco addiction cessation. Children and non-smokers are warned against vaping.

FTX's bankruptcy lawyers announced that customers will recover all lost funds with interest after the firm's $8 billion collapse in 2022. Creditors, including ordinary investors, will receive 118% of their assets. Despite recent crypto market surges, payments are based on 2022 asset values. For example, a customer who lost one Bitcoin could expect less than $20,000, even though Bitcoin's current value exceeds $60,000.

Extreme weather events have hit multiple countries, with record-breaking temperatures and flooding. In Brazil, flooding killed dozens, while India faced 115-degree heat. The Philippines, Thailand, Indonesia, Malaysia, and Myanmar experienced a brutal heatwave. The US saw high tornado numbers in April. Climate scientists warn of worsening disasters due to global warming. 70 countries broke heat records in early May. Africa and Latin America also faced scorching temperatures.

A study reveals that approximately 124 million Americans spend an hour daily in cars containing carcinogenic flame retardant chemicals. These chemicals, mandated since the 1970s, are linked to health risks and potential carcinogens. Exposure to these chemicals has led to IQ loss in children and increased cancer risk in adults. Firefighters are concerned about the impact on their health. The study emphasizes the need for reforms to ensure safety.

The Oxford-AstraZeneca Covid vaccine is being globally withdrawn due to rare side effects. The European Union has already stopped its use. AstraZeneca cited commercial reasons for the withdrawal, as updated vaccines are available. The vaccine's side effect, causing blood clots and low platelet counts, led to at least 81 deaths in the UK. Lawsuits are ongoing with over 50 claimants.

Ukraine foiled a Russian plot to assassinate President Zelensky, detaining two Ukrainian security officials involved. The plan involved targeting top Ukrainian officials with rocket attacks and drones. The arrested colonels were recruited before Russia's 2022 invasion. President Zelensky had faced at least 10 previous assassination attempts. The operation was overseen by Ukraine's State Security Service. Prosecutors in Poland also uncovered a related espionage plot.

Microsoft is developing a new AI model, MAI-1, with 500 billion parameters, aiming to compete with Google, Anthropic, and OpenAI. Spearheaded by ex-Google AI chief Mustafa Suleyman, the project signifies Microsoft's commitment to AI. Suleyman, now Microsoft's AI CEO, co-founded DeepMind and Inflection AI. Microsoft acquired Inflection's team for USD 650 million. MAI-1's development marks a significant step in Microsoft's AI endeavors.

Boeing is set to launch its first crewed Starliner spacecraft after years of development. The launch, in partnership with NASA, is scheduled for May 6 at 10:34 pm EDT. The livestream begins at 6:30 pm Eastern. If successful, Boeing will be the second company to carry humans into space for NASA. The mission aims to bring astronauts to the International Space Station and back.

SpaceX's upcoming Polaris Dawn mission will feature the first private astronaut extravehicular activity (EVA) tasks. The new EVA spacesuit, unveiled recently, includes material enhancements and a heads-up display in the helmet. The mission, funded by Jared Isaacman, aims to raise money for St. Jude Children's Research Hospital and push the boundaries of human spaceflight. Polaris Dawn will last five days, with up to 40 experiments planned.

Skydance, with support from James Cameron and Ari Emanuel, aims to acquire Paramount. The deal involves RedBird Capital and KKIR, merging Skydance into Paramount. Cameron praises David Ellison's leadership potential. Meanwhile, Paramount considers a $26 billion offer from Apollo and Sony Pictures. Amidst changes, Paramount's new CEOs are preparing a strategic plan for the future. Talks between Skydance and Paramount continue.

Pro-Palestinian protests in US universities have spread globally, with demonstrations in the UK, France, Australia, and more. Over a million people displaced by the conflict in Gaza are sheltering in Rafah, facing a humanitarian crisis. The war has killed over 34,500 Palestinians. Support for Israel's military assault has dropped in the US. Messages of gratitude from Gaza to protesting students worldwide have been shared.

iOS 18 will heavily feature AI capabilities, including generative AI from Ajax LLM. New leaks suggest AI-powered text summarization for Safari and Siri. Ajax can generate responses locally for privacy and speed, with responses in milliseconds. Tight integration with Apple apps is expected. Privacy warnings will be shown for data access. Expect more AI enhancements across iOS and macOS at WWDC 2024 in June.

Xi Jinping visits Europe to ease tensions and avoid a trade war with the EU. He faces trade talks in France and Ukraine, aiming to counter EU investigations into Chinese companies. Preliminary duties on Chinese electric vehicle imports could be imposed in May. Xi's visit to Hungary promises significant Chinese investment. Macron seeks Xi's influence on Russia amid the Ukraine conflict. EU-China relations and trade deficits are key concerns.

Houston faced severe flooding with over 300 people rescued due to heavy rains. The San Jacinto River caused water levels to rise from 1 to 4 feet. A flood watch was in effect with 1 to 3 inches of additional rainfall predicted. Houston, a flood-prone area, has a history of dealing with devastating weather. Shelters have opened, and evacuations were ordered along the river. Reservoirs and ground saturation exacerbated the situation.

Boeing faces Congressional probes and whistleblower deaths. Joshua Dean and John Barnett, whistleblowers, found dead under mysterious circumstances. Concerns arise about possible foul play. Boeing reports $355 million loss in Q1. CEO Dave Calhoun resigns amid safety concerns. Lawyers seek extensive investigation into deaths. Boeing spokesman emphasizes no retaliation for whistleblowers. Former Boeing manager criticizes company's failure to admit truth about safety issues. Two 737 Max disasters blamed on Boeing failures.

The USDA detected bird flu in dairy cattle in nine states, with 36 confirmed outbreaks. The virus has spread between cows and herds, with potential underreporting. FDA found viral fragments in 1 in 5 retail milk samples. Human infections are rare but fatal, with one confirmed case in Texas. Undocumented dairy workers pose a challenge for tracking infections. Lack of incentives for reporting infections increases the risk of spread.

NASA's superalloy GRX-810, designed for extreme air and space conditions, will be licensed to four U.S. companies. The 3D-printable material offers stronger, more durable parts for airplanes and spacecraft, enduring over 2,000°F temperatures. GRX-810 lasts 2,500 times longer than other alloys, improves fuel efficiency, and lowers operating costs. NASA's Technology Transfer Program aims to commercialize inventions for the benefit of the U.S. economy.

A study reveals a blood test can detect knee osteoarthritis up to 8 years earlier than X-rays, predicting the condition with 77% accuracy using 6 bloodborne proteins. This breakthrough could lead to early preventive strategies for the 32.5 million affected adults in the US. Dr. Kraus suggests targeting these proteins for improved preventative treatments. Clinical trials may follow to assess new medications' effectiveness in halting osteoarthritis progression.

Currys partners with Microsoft and Accenture to implement AI technologies, enhancing operations and customer experiences. The transition includes moving data centers to Azure for energy efficiency. Benefits include personalized shopping experiences, improved post-sales services, and increased productivity. Currys aims to achieve net zero emissions by 2040. Executives from Currys, Accenture, and Microsoft express optimism about the partnership's potential for digital transformation and growth in the retail industry.

NASA's Artemis III mission in 2026 will study plant growth on the Moon using the Lunar Effects on Agricultural Flora (LEAF) experiment. Plants like thale cress, duckweed, and Brassica rapa will be grown in a protected chamber to analyze their response to lunar conditions. Success could lead to sustainable habitats in space. The mission will explore the Moon's south pole, aiming to advance humanity's space exploration journey.

BBVA made a 12.23 billion euro takeover bid for Sabadell, despite Sabadell's board rejecting it. BBVA's offer includes a 30% premium over April 29 closing prices, with an exchange ratio of 1 BBVA share for every 4.83 Sabadell shares. This move aims to create a larger bank in Spain's market. Hostile takeovers are uncommon in European banking. Spanish banks seek revenue growth due to declining interest rates.

Putin accuses the West of risking global conflict, stating Russia's forces are at 'combat readiness'. Ukraine's air defense destroyed 17 out of 20 Russian attack drones. Ukraine parliament dismissed agriculture minister amid land acquisition allegations. David Cameron urges the West to be tougher in response to Russia's invasion of Ukraine. A Ukrainian air attack on Russia's Belgorod region injured eight people and damaged buildings and cars.

Researchers at Karolinska Institutet and Pixelgen Technologies have introduced a groundbreaking technique, molecular pixelation, enabling the mapping of hundreds of proteins in individual cells simultaneously. This advancement allows for a detailed analysis of protein distribution and interactions within cells, crucial for studying diseases like cancer. Funded by Knut and Alice Wallenberg Foundation, Swedish Society for Medical Research, and Swedish Research Council, the technology is being commercialized by Pixelgen.

Western Australians benefit from a $3.2 billion budget surplus, with economic growth at 5.25%. Homeless people receive an extra $92 million in funding. Households save on costs with $762 million allocated. Health sector gets $3.2 billion for hospital capacity. Parents receive cash incentives for school children. Small businesses miss out on payroll tax relief. Apprentices in building and construction receive financial support. Environment sees investments in climate action and renewable energy. Young detainees and Metronet face funding challenges.

A survey by Which? revealed 32% of buyers were scammed on secondhand marketplaces in the past two years. APP fraud cases totaled 77,000 in the first half of 2023, with £41m lost. Depop had the highest scam rate at 57%, followed by Shpock at 53% and Preloved at 51%. Amazon Marketplace had a 35% scam rate. Marketplaces are urged to enhance security measures.

The US, Australia, Japan, and the Philippines form an informal alliance called the "Squad" to counter China's assertiveness. The group aims to strengthen ties and enhance security cooperation. Analysts predict the Squad may evolve into a more formalized bloc like the Quad. The Philippines benefits from security assistance and elevated status. India's focus remains on its own region, with recent military cooperation with the Philippines.

Queensland's Labor government is quadrupling the Stanwell battery's storage capacity to 1,200 MWh, making it the state's largest battery project. Built by Tesla for $747 million, it will support renewable energy targets. The state aims for 80% renewables by 2035, currently at 27%. The battery is part of a clean energy hub, with more batteries planned. The government emphasizes job creation and economic growth.

A team from the University of Cambridge developed a thin, flexible electronic device that wraps around the spinal cord to record nerve signals. The device can provide 360-degree information, stimulate limb movement, and bypass complete spinal cord injuries. This innovation could lead to safer treatments for spinal injuries without brain surgery. The research, supported by various organizations, was published in Science Advances.

Witnesses detail the RSF's massacre of civilians in Darfur, with thousands killed in ethnic violence. HRW calls for an arms embargo on Sudan and sanctions on RSF commanders. Over 8 million displaced since April 2023. El Fasher faces a potential large-scale massacre. HRW urges action to prevent further atrocities. Testimonies include children being shot and piled up. HRW documents attacks on civilians and medical clinics.

Prime Minister Shehbaz Sharif declared an education emergency in Pakistan to address the challenge of 26 million out-of-school children. Unicef reported that over 70% of Pakistani children aged 10 cannot read or understand text. The country aims to become one of the most educated societies globally. Urgent actions are needed to improve education, with a focus on enrollment, literacy, and financial resources. Various stakeholders, including international partners, support this initiative.

In May 2024, Pakistan faced a concerning polio outbreak with wild poliovirus type 1 found in Hub's sewage samples, previously a virus-free district. 116 cases were reported this year, with 34 districts affected. The virus is linked to an imported genetic cluster. The Pakistan Polio Programme conducted four vaccination campaigns, reaching over 43 million children. The next campaign is planned for June. Vaccination is crucial to prevent polio's spread.

Up to 40% of mental health conditions in Australia, such as anxiety and depression, are linked to childhood maltreatment. Addressing this issue could prevent over 1.8 million cases of these disorders. Childhood maltreatment contributes to 41% of suicide attempts and 35% of self-harm cases nationally. Urgent policy interventions are needed to prioritize childhood abuse prevention as a public health priority.

Disney and Warner Bros. Discovery are launching a streaming bundle this summer, combining Disney+, Hulu, and Max. Pricing details are pending, with ad-free and ad-supported options available. The companies tout the bundle as the "best value in entertainment," filling a unique market niche. This partnership marks a departure for Disney, previously relying on its own bundles. Both companies are key players in an upcoming sports streaming service.

Children with chronic sleep deprivation from infancy to early childhood are over twice as likely to develop psychotic disorders and nearly four times as likely to experience psychotic episodes in early adulthood. The study, based on the Avon Longitudinal Study of Parents and Children, suggests a strong link between persistent lack of sleep and psychosis. Potential biological explanations include immune system impairments. Early intervention in sleep issues may help prevent mental health problems.

OpenAI is introducing Model Spec, a framework for AI behavior, aiming to guide responses of tools like GPT-4. It emphasizes assisting users, benefiting humanity, and adhering to laws and social norms. Rules include following a chain of command, respecting privacy, and avoiding NSFW content. OpenAI seeks public input to refine the framework, which won't immediately affect existing models. Model Spec is a dynamic document open to updates.

Researchers at UCLA discovered a brain mechanism enhancing memory formation while reducing energy consumption during sleep in the entorhinal cortex, crucial for learning and Alzheimer's onset. Using a novel mathematical model, they found a way to maintain memory states with less energy, potentially aiding early Alzheimer's diagnosis. The study, published in Nature Communications, reveals a new memory state called spontaneous persistent inactivity, doubling memory capacity while halving metabolic energy cost.

A study suggests doubling daily physical activity for optimal cardiometabolic health. Australian research provides an hour-by-hour breakdown to reduce risks. Most Australians sit for 8 hours and only get 2 hours of physical activity daily. The study analyzed over 2,000 people, recommending less sitting and more movement. Researchers hope findings will update health guidelines. Different activities impact health differently, requiring personalized time allocation.

CAR-T cell therapy has transformed blood cancer treatment in the last decade. A new study by Dr. Xingxing Zang introduces TOP CAR, a more potent version targeting solid tumors. In animal trials, TOP CAR showed improved survival rates compared to existing CAR-T therapies. Zang's innovative approach includes a new co-stimulator, TMIGD2, yielding promising results. This advancement could lead to clinical trials for solid tumors resistant to current treatments.

Tornadoes are increasingly forming in packs, with over a dozen reported in the Great Plains and Midwest this week. The Storm Prediction Center noted hundreds forming on the worst days. In April, 105 tornadoes were reported on the most active day. Such outbreaks, though not new, are becoming more frequent in recent decades.

A high-severity flaw in LiteSpeed Cache plugin for WordPress, tracked as CVE-2023-40000, allows hackers to create admin accounts by injecting malicious JavaScript. Over 1.8 million users are at risk with versions 5.7.0.1 or older. The current version, 6.2.0.1, is secure. One threat actor made over a million probing requests in April 2024. Users are urged to update to the latest version and remove unused plugins and themes.

Summary: A study reveals how psychedelics interact with serotonin receptors, particularly 5-HT1A, offering potential non-hallucinogenic treatments for depression and anxiety. A synthesized compound, 4-F, 5-MeO-PyrT, showed antidepressant effects through 5-HT1A activation. This research could lead to new therapies leveraging psychedelics' therapeutic benefits while minimizing psychoactive effects, impacting mental health treatment significantly. Key Facts: - Psychedelics engage with 5-HT1A alongside 5-HT2A for therapeutic outcomes. - A synthesized compound, 4-F, 5-MeO-PyrT, showed antidepressant effects through 5-HT1A activation. - Research could lead to new treatments for mental health disorders using psychedelics' therapeutic potentials while minimizing psychoactive effects.

NASA plans to send astronauts back to the moon in 2025, aiming to establish a permanent lunar base. To combat muscle and bone loss in low-gravity conditions, researchers propose astronauts run on a "Wall of Death" at 8 mph, simulating lunar gravity. This exercise could counteract whole-body deconditioning. However, logistical challenges remain, and alternative training methods may be necessary due to space constraints on the moon.

A clinical trial supported by NIH's NIDA found starting opioid use disorder patients on XR-naltrexone within 5-7 days of seeking treatment is more effective than the standard 10-15 days. The rapid approach increased first injections by 62.7% compared to 35.8%. The study, SWIFT, aimed to make XR-naltrexone more viable as an opioid use disorder treatment option. Over 107,000 people died of drug overdoses in 2022, with 75% involving opioids.

The world's largest direct air capture plant, "Mammoth," in Iceland, operated by Climeworks, can capture 36,000 tons of carbon annually. The plant uses geothermal energy and plans to scale up to 1 million tons by 2030 and 1 billion tons by 2050. Despite concerns about costs and energy use, such technologies are crucial as global carbon dioxide levels hit record highs in 2023.

A study led by Yale pharmacologist Benjamin Turk focused on understanding the roles of tyrosine kinases, crucial for cell communication and often implicated in cancer. The research, published in Nature, developed tools to identify kinase functions and signaling patterns. With 78 tyrosine kinases in humans, the study revealed insights into kinase activity and potential cancer treatments. Understanding kinase specificity is key for developing effective therapies.

AI usage in the workplace is rising, with 75% of workers using it, but concerns about job replacement persist. Microsoft and LinkedIn's research surveyed 31,000 people across 31 countries, revealing that over half of users fear being replaced. Nearly half of professionals worry about AI taking their jobs and consider leaving. Experts advise embracing AI to enhance job marketability and skills.