Whole genome sequencing explains 88% of human trait heritability

Whole genome sequencing in nearly 500,000 individuals explains 88% of heritability for many human traits. Researchers found that rare and common genetic variants, including those in coding regions, now account for most of the previously unexplained heritability for traits like height and lipids. Ultra-rare variants, structural variations, and limitations in genome builds are suspected causes for the remaining heritability gap.