Urine test detects tuberculosis antigens in extracellular vesicles

A new urine test shows promise for diagnosing pulmonary tuberculosis non-invasively. Researchers developed a real-time immuno-PCR assay using urinary extracellular vesicles to detect TB antigens, achieving high sensitivity and specificity in a study of 162 participants. This method could offer a more accessible diagnostic tool for tuberculosis, especially in resource-limited settings, though further large-scale trials are needed.