University of Bath researchers develop bacterial system to discover peptide drugs for hard-to-treat cancers

University of Bath researchers developed a bacterial system to rapidly discover and stabilize peptide drug candidates for hard-to-treat cancers. This innovative technology uses bacteria to produce, chemically stabilize, and test millions of peptide molecules inside living cells, identifying effective and non-toxic drug candidates. The system has successfully identified peptide inhibitors for the CREB1 transcription factor, which is overactive in various cancers, and demonstrated their ability to kill cancer cells in lab tests.