Study reveals rare brain cells influence aging and rejuvenation processes

A new study published in *Nature* reveals that interactions between rare brain cell types significantly influence aging. Neural stem cells can rejuvenate nearby cells, while T cells promote aging through inflammation. Researchers used advanced AI tools to analyze these interactions in mice. The study highlights the importance of cellular neighborhoods in the aging process, moving beyond previous research that focused on individual cells. By mapping gene activity across various life stages, the team identified how specific cell types affect each other. These findings may lead to new strategies for combating neurodegeneration and cognitive decline. The research team plans to extend their approach to human tissues and explore potential interventions to enhance the effects of beneficial cells.