Skin cancer cells reprogram healthy cells to fuel tumor growth

futurity.org

Skin cancer cells transfer mitochondria to healthy neighboring cells, reprogramming them to support tumor growth. This transfer occurs via tiny tubes, turning healthy fibroblasts into tumor-associated fibroblasts that boost cancer cell proliferation and alter the tumor environment. Researchers identified the protein MIRO2 as crucial for this process, suggesting it as a potential target for future cancer therapies.


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Skin cancer cells reprogram healthy cells to fuel tumor growth | News Minimalist