Single dose of DMT with psychotherapy offers lasting relief for severe depression

A single dose of the psychedelic drug DMT, combined with psychotherapy, has shown lasting relief for severe depression symptoms in a phase 2 trial. The 25-minute DMT experience proved safe and effective, with results comparable to other psychedelic treatments that require longer sessions. Researchers suggest DMT, like psilocybin, may enhance brain plasticity. This controlled therapeutic approach is emphasized as crucial for safety, contrasting with potentially dangerous recreational use of psychedelics.