Scientists rapidly reprogram proteins with an evolution engine

phys.org

Scientists have developed an "evolution engine" that rapidly reprograms proteins, accelerating evolution thousands of times faster than nature. The T7-ORACLE system uses an artificial DNA replication system in E. coli bacteria, introducing mutations at an extremely high rate without harming the host cell's genome. This allows for rapid protein engineering for various diseases. This breakthrough platform is adaptable for evolving virtually any protein, potentially aiding in the development of new cancer therapies and treatments for neurodegenerative diseases.


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Scientists rapidly reprogram proteins with an evolution engine | News Minimalist