Restoring NAD+ levels reverses Alzheimer's pathology in mouse models

neurosciencenews.com

A new study suggests Alzheimer's disease may be reversible by restoring a key energy molecule. Researchers found a severe drop in NAD+ drives Alzheimer's pathology. Restoring NAD+ balance with the drug P7C3-A20 reversed brain damage and cognitive decline in mouse models, even in advanced stages of the disease. This finding challenges the long-held view that Alzheimer's is irreversible, offering hope for future treatments focused on recovery rather than just slowing progression.


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