Researchers uncover how Sudan virus binds to human cells more effectively than Ebola

news-medical.net February 4, 2025, 08:00 PM UTC

Researchers at the University of Minnesota have made new discoveries about how the Sudan virus attaches to human cells. This virus, related to Ebola, has a 50% fatality rate and currently has no approved treatments. Using advanced imaging techniques, the team found that the Sudan virus binds to a protein called NPC1 with nine times greater strength than Ebola. This stronger binding may explain its higher fatality rate. The study also explored how the Sudan virus interacts with NPC1 in bats, its natural hosts. These findings enhance understanding of the virus's infection methods and could lead to potential treatments.


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