Researchers identify protein USP50 as crucial for DNA replication balance

Researchers have identified a protein called USP50 that plays a crucial role in DNA replication. This protein helps determine which enzymes, known as nucleases and helicases, are used during the replication process. The study, published in *Nature Communications*, shows that USP50 ensures proper enzyme selection, which is vital for maintaining DNA integrity. Without USP50, cells struggle to coordinate these enzymes, leading to replication errors. This discovery enhances understanding of DNA replication and may provide insights into hereditary conditions, including early aging and cancer.