Radiation for rectal cancer balances survival, stoma risk

Presurgical radiation for locally advanced rectal cancer improves overall survival, but increases the risk of a permanent diverting stoma, according to new research. This trade-off varies based on tumor location. The study found that while radiation improved survival overall, patients with upper rectal cancers did not benefit and faced the highest risk of permanent stomas. The research analyzed data from nearly 3800 patients. Experts emphasize the need to consider tumor height when deciding on radiation. They also note that overtreatment with radiation is possible, and that treatment should be tailored to the individual patient's circumstances.