Protein cluster discovery may aid muscular dystrophy treatments

Researchers at USC Dornsife have discovered how tiny protein clusters, specifically emerin, form in cells. This finding could lead to new treatments for Emery-Dreifuss muscular dystrophy (EDMD), a genetic disorder causing muscle weakness and heart issues. The study reveals the molecular rules behind emerin's arrangement and how defects in this process contribute to EDMD. By understanding these mechanisms, scientists aim to develop strategies to correct the defects affecting cellular responses to mechanical forces. The research applies principles from Alan Turing's work on pattern formation to protein assembly. This approach may also provide insights into other diseases related to cellular mechanics.