New research shows brain cells age differently, revealing cell-specific patterns

New research funded by the National Institutes of Health reveals that different cell types in the brain age differently. Some hormone-controlling cells show more significant age-related changes in genetic activity compared to others, suggesting varying sensitivity to aging. Scientists analyzed brain cells from young and aged mice, finding decreased activity in genes linked to neuronal circuits and increased activity in genes related to immunity and inflammation. The most affected cells were near the third ventricle, which regulates hormones and basic body functions. These findings may change how researchers understand brain aging and could guide future treatments for age-related brain disorders. Further studies are needed to explore the biological mechanisms and potential connections to human health.