New CRISPR system offers irreversible control over engineered microbes for enhanced biosafety

phys.org

New CRISPR technology offers irreversible control over engineered microbes, enhancing biosafety. Researchers developed a base-editing system that precisely disables essential genes without DNA breaks, preventing unintended release and proliferation of engineered microorganisms. This innovation reduces mutations and escape frequency, promising safer applications in industrial biotechnology, biopharmaceuticals, and future cell-based medicines.


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New CRISPR system offers irreversible control over engineered microbes for enhanced biosafety | News Minimalist