New antibody therapy may replace chemotherapy for cancer

Scientists have developed a new antibody therapy, IgE, that may replace chemotherapy for treating certain cancers, particularly those expressing the HER2 marker. This therapy activates the immune system differently than the commonly used IgG antibodies. In tests on mice, IgE antibodies effectively targeted HER2-expressing cancer cells and slowed tumor growth, even in cases resistant to traditional treatments. The therapy reprogrammed the tumor's immune environment to stimulate an immune response against the cancer. Researchers believe that with further development, IgE therapy could be available for human use in 3-5 years, offering new hope for patients with HER2-positive cancers that do not respond to existing therapies.