New algorithm visualizes cell communication across tissue and time

A new algorithm visualizes cell-to-cell communication in tissues over time. This breakthrough allows scientists to map how cells signal each other, a process previously difficult to track. The algorithm, CytoSignal, uses spatial transcriptomics data to infer which cells are communicating and how. It can distinguish between direct contact and signal diffusion, offering a more comprehensive understanding of cellular interactions. This advancement has potential applications in understanding disease mechanisms and developing new drug treatments by identifying disrupted signaling pathways.