GLP-1 drug withdrawal causes weight regain and health decline in most users, study finds

arstechnica.com

A new study suggests that stopping GLP-1 weight-loss drugs may lead to significant weight regain and reversal of cardiovascular health improvements for most users. The analysis found 82% of participants regained substantial weight after discontinuing tirzepatide, with a corresponding decline in blood pressure, cholesterol, and glucose control. Experts recommend these drugs be viewed as long-term weight management tools, similar to medications for chronic diseases, due to the lack of clear "off-ramps."


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