Estrogen depletion accelerates Alzheimer's risk in postmenopausal women

Postmenopausal hormone changes are linked to an irreversible Alzheimer's disease risk in women. A new study suggests estrogen depletion accelerates brain matrix collapse, making women uniquely sensitive to Alzheimer's. This could lead to new treatments. Women account for two-thirds of Alzheimer's cases. The research focused on the brain's extracellular matrix, a shift from traditional approaches.