CRISPR method controls protein production speed to regulate cell behavior

Scientists developed a new CRISPR method to control protein production speed in cells. This advancement allows targeted manipulation of ribosomal RNA (rRNA) levels. The method, called TAPIR, directly links rRNA amount to cell division, specialization, and stem cell properties. Researchers demonstrated that activating rRNA production significantly boosts protein synthesis. This breakthrough offers new perspectives for treating rare diseases like Treacher-Collins syndrome and understanding pancreatic cancer growth, potentially leading to novel therapeutic strategies.