Christina Applegate reveals early multiple sclerosis symptoms while filming Dead to Me pilot

Christina Applegate revealed she experienced early symptoms of multiple sclerosis (MS) while filming the pilot of "Dead to Me." During a podcast episode, she recalled falling while running, which she now recognizes as a sign of her condition. Applegate, diagnosed with MS in 2021, discussed how her health impacted the show's production. Although her illness was not written into her character's storyline, she described filming the final episodes as extremely challenging. Production was paused to prioritize Applegate's health, but she insisted on completing the series on her own terms. She shared that she was brought to the set in a wheelchair for the final scenes.