Cellular stress promotes cancer by altering gut microbiome and lipid metabolism

medicalxpress.com

Chronic cellular stress activates a protein, ATF6, altering gut lipid metabolism and promoting cancer. This change increases long-chain fatty acids, feeding specific bacteria like Desulfovibrio fairfieldensis, which displace other microbes and can damage the gut. The findings, observed in mice and human cancer patients, suggest a link between cellular stress, microbiome shifts, and cancer development.


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Cellular stress promotes cancer by altering gut microbiome and lipid metabolism | News Minimalist