Cancer cells steal iron, causing anemia, bone metastasis

news-medical.net

Breast cancer cells hijack iron-handling macrophages in bone marrow, causing anemia and promoting metastasis. Researchers found these cancer cells steal iron from red blood cell precursors, disrupting their function and enabling tumor growth in the oxygen-poor bone marrow environment. This discovery reveals a new pathway for tumor-immune-metabolic interaction, potentially leading to therapies that target tumor growth and alleviate anemia in cancer patients.


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