Brain atrophy patterns predict Parkinson's, Lewy body dementia

Researchers have identified distinct brain atrophy patterns that may predict the progression of Parkinson's disease and Lewy body dementia. This discovery could lead to earlier diagnoses and improved patient care. A study of individuals with REM Sleep Behavior Disorder (RBD), a precursor to these neurodegenerative diseases, revealed two different trajectories of brain atrophy. These patterns, identified using AI and MRI scans, could help differentiate between Parkinson's and LBD. The research team hopes to use these findings to develop more reliable biomarkers for diagnosis. They aim to understand the factors driving these brain changes and ultimately improve treatment options for patients.