Baxdrostat shows lasting blood pressure benefits two years after treatment ends

A new drug, baxdrostat, has shown unexpected long-term benefits for high blood pressure, with effects lasting up to two years after patients stop taking it, potentially curing some cases. The drug targets primary aldosteronism, a condition caused by adrenal gland nodules overproducing aldosterone, which affects 5-10% of hypertension patients. In a small study of 14 patients, nearly a quarter achieved normal blood pressure without any medication after treatment. Baxdrostat is already approved in the US and under NHS assessment in the UK. Researchers suspect the drug destroys hormone-producing cells through reactive oxygen species, though larger trials are needed to confirm a cure.