Nanomedicine developed to combat HIV transmission and replication

University of Waterloo's Emmanuel Ho developed a nanomedicine using small interfering RNAs (siRNA) to combat HIV, showing a 73% reduction in HIV replication. The nanomedicine reactivates autophagy and targets HIV entry genes. It's designed for vaginal application to prevent sexual transmission, stable in the acidic environment, and releases siRNA inside cells. Ho plans to optimize the process and explore alternative approaches to reduce antimicrobial resistance.